Real time monitoring of various metabolic analytes that control body’s function and physiology is important for diabetic patients in everyday life.  This hinges on the development of a biosensor capable of continuously monitoring in an autonomous mode, and yet does not interfere with the activity of the user.  A promising category of such sensors, which has been actively pursued during the past decades, is implantable devices.  Although numerous sensory devices have functioned adequately when tested in vitro, these systems usually fail after a few days of in vivo implantation.  A combination of negative tissues responses along with the necessity for skin-protruding external leads are considered among the most significant factors responsible for loss of in vivo device functionality.  The latter can be avoided by miniaturization of not only the sensor, but also the detection electronics, power supply and transmission module needed to report the data to an external monitoring system.  The key to GLUCOWIZZARD^TM success is device miniaturization and suppression of negative tissue responses to ensure long term in vivo functionality. GLUCOWIZZARD^TM will soon become available for use on drug discovery in the field of diabetes and glucose related disorders.  GLUCOWIZZARD^TM line of products, designed for drug development, are used for testing drugs and chemicals for their effect related to certain disorders (e.g., diabetes, cardiovascular).  Pharmaceutical companies and researchers can use our sensor platform for drug discovery and disease study, especially since our technology provides both an economical and scientific competitive advantage to the user.

Advantages of Biorasis Inc. bio-analyte sensing platform for any of your needs in Drug-Discovery and metabloic monitoring:

1. Continuous monitoring of bio-analyte levels in experimental animals, eliminating the need of blood sampling, which is challenging in small animals (rodents).
2. Continuous monitoring of bio-analyte levels without anesthetizing the animal, thereby avoiding the inevitable bio-analyte fluctuations induced by anesthesia.
3. Testing of bio-analyte levels under any  experimental conditions (e.g., rest, exercise, stress, etc) and under various treatments involving a variety of pharmaceutical agents.
4. A significant reduction in the cost of animal experimentation, bypassing the need of anesthesia, needles, pricking, and various bio-analyte monitoring kits.
5. Remote monitoring of bio-analyte levels and significantly reducing the time for experimentation and eventually for drug development.
6. Biorasis Inc. can adopt its implantable bio-analyte platform to monitor other disease complications, such as cardiovascular, cancer, stroke, epilepsy, liver and kidney disorders.  Biorasis Inc. sensor platform can be used in drug development and other studies in a number of disorders and can be adopted to the needs of our customers.
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